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DNA–peptide complexes

Regulation of interferon production

Nature Materials volume 14, pages 661–662 (2015)Cite this article

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DNA spacing within hexagonal bundles of DNA and polycationic peptides correlates with interferon production in dendritic cells.

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Figure 1: DNA/cationic peptide structures.
Figure 2: Normalized concentrations of IFN-α produced by dendritic cells incubated with each of 15 different in vitro reconstituted complexes of DNA and polyvalent cation, as a function of the position of the first peak in the corresponding SAXS profile of the complex.

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Authors and Affiliations

  1. William M. Gelbart is in the Department of Chemistry and Biochemistry, University of California Los Angeles, 607 Charles E. Young Drive, Los Angeles, California 90095-1569, USA,

    William M. Gelbart

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  1. William M. Gelbart
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Correspondence to William M. Gelbart.

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Gelbart, W. Regulation of interferon production. Nature Mater 14, 661–662 (2015). https://doi.org/10.1038/nmat4332

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