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Cell mechanics

Hydraulic cracking

Cracks in stretched epithelial tissue are caused by a build-up of hydraulic pressure beneath the cells when the tissue is unloaded.

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Figure 1: Cracking of an epithelial cell monolayer after stretch and subsequent release.
Figure 2: Subcellular cracking during blebbing.

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Correspondence to Emad Moeendarbary or Guillaume Charras.

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Moeendarbary, E., Charras, G. Hydraulic cracking. Nature Mater 14, 268–269 (2015). https://doi.org/10.1038/nmat4229

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