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Protein-patterned hydrogels

Customized cell microenvironments

Mimicking the complexity of the extracellular environment in synthetic hydrogels is hard. A simple two-photon excitation strategy to simultaneously immobilize multiple proteins with spatial control in three dimensions shows promise.

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Figure 1: Mimicking the extracellular environment in synthetic hydrogels.

DONALD SOWARD/RICE UNIVERSITY

Figure 2: Simultaneous immobilization of multiple proteins in 3D hydrogels.

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Correspondence to Jennifer L. West.

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West, J. Customized cell microenvironments. Nature Mater 10, 727–729 (2011). https://doi.org/10.1038/nmat3132

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