Reduction in blood levels of low-density lipoprotein cholesterol reduces the risk of coronary heart disease. The identification of a new class of compounds that upregulate the low-density lipoprotein receptor may lead to new therapeutic advances. (pages 1332–1338)
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Platycodin D enhances LDLR expression and LDL uptake via down-regulation of IDOL mRNA in hepatic cells
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Rader, D. A new feature on the cholesterol-lowering landscape. Nat Med 7, 1282–1284 (2001). https://doi.org/10.1038/nm1201-1282
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DOI: https://doi.org/10.1038/nm1201-1282
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