Hematopoietic stem cells maintain the capacity for self-renewal despite the hazard of oxidative damage. Studies in mice show that this hazard is held in check by the ataxia telangiectasia mutated gene, operating through some well-known tumor suppressors.
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References
McKinnon, P.J. EMBO Reports 5, 772–776 (2004).
Shiloh, Y. Nat. Rev. Cancer 3, 155–168 (2003).
Ito, K et al. Nature 433, 997–1002 (2004).
Friedman, J.S. et al. J. Exp. Med. 193, 925–934 (2001).
Nilsson, S.K. et al. Blood 97, 2293–2299 (2001).
Arai, D. et al. Cell 118, 149–161 (2004).
Danet, G.H. et al. J. Clin. Invest. 112, 126–135 (2003).
Ivanovic, Z. et al. Stem Cells 22, 716–724 (2004).
Krosl, J. et al. Nat. Med. 9, 1428–1432 (2003).
Park, I.K. et al. Nature 423, 302–305 (2003).
Wong, K.K. et al. Nature 421, 643–648 (2003).
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Whetton, A. Stem cells bank on ATM machine. Nat Med 10, 1166–1168 (2004). https://doi.org/10.1038/nm1104-1166
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DOI: https://doi.org/10.1038/nm1104-1166
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