Abstract
Although CD4+ and CD8+ T cells are known to be involved in autoimmune diabetes, their exact mechanism is unknown. Wong et al. identify the insulin B chain as the antigen recognized by autoimmune CD8+ T cells capable of inducing diabetes (pages 1026–1031).
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Benoist, C., Mathis, D. Spotting a killer's target in autoimmune diabetes. Nat Med 5, 992–993 (1999). https://doi.org/10.1038/12428
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DOI: https://doi.org/10.1038/12428
