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From Agouti to Pomc—100 years of fat blonde mice

Abstract

Studies of mice deficient for proopiomelanocortin (Pomc) yield surprising results, and finally take us beyond the Ay model of melanocortin deficiency (pages 1066–1070).

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Figure 1: Melanocortin physiology and pathophysiology in Pomc knockout mice.

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Barsh, G. From Agouti to Pomc—100 years of fat blonde mice. Nat Med 5, 984–985 (1999). https://doi.org/10.1038/12415

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