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Ibuprofen, inflammation and Alzheimer disease

Nature Medicine volume 6, pages 973–974 (2000)Cite this article

Mounting evidence suggests that non-steroidal anti-inflammatory drugs may be useful in reducing the risk of Alzheimer disease. After much study, the mechanism by which these drugs reduce the amyloid deposition associated with the disease is still open to speculation.

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Figure 1: Potential effects of ibuprofen on AD-type pathology.

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Authors and Affiliations

  1. Gladstone Institute of Neurological Disease and Department of Neurology, University of California, San Francisco, 94141, California

    Tony Wyss-Coray & Lennart Mucke

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  1. Tony Wyss-Coray
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  2. Lennart Mucke
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Wyss-Coray, T., Mucke, L. Ibuprofen, inflammation and Alzheimer disease. Nat Med 6, 973–974 (2000). https://doi.org/10.1038/79661

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