Emerging data has indicated that supervised treatment interruption (STI) of highly active antiretroviral therapy might significantly augment immune responses in HIV-1-infected patients and slow disease progression. Here the authors discuss the rationale behind STI and future directions for study.
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On the role of resonance in drug failure under HIV treatment interruption
Theoretical Biology and Medical Modelling Open Access 11 July 2013
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Altfeld, M., Walker, B. Less is more? STI in acute and chronic HIV-1 infection. Nat Med 7, 881–884 (2001). https://doi.org/10.1038/90901
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DOI: https://doi.org/10.1038/90901
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