Loss of response to TGF-βs may be an important step in the development and progression of cancer. Recent studies show that receptors and proteins involved in TGF-β signaling may act as tumor suppressors.
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Serra, R., Moses, H. Tumor suppressor genes in the TGF–β signaling pathway?. Nat Med 2, 390–391 (1996). https://doi.org/10.1038/nm0496-390
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DOI: https://doi.org/10.1038/nm0496-390
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