Two studies examine the cellular origins of peripheral nervous system tumors in mouse models of neurofibromatosis type 1 and conclude that stem cells may not be the culprits. Instead, more differentiated cells may give rise to and drive the tumors.
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Dirks, P. Cancer's source in the peripheral nervous system. Nat Med 14, 373–375 (2008). https://doi.org/10.1038/nm0408-373
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DOI: https://doi.org/10.1038/nm0408-373
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