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Remodeling after stroke

Nature Medicine volume 12, pages 390–391 (2006)Cite this article

A promising approach to treating ischemic stroke, inhibition of matrix metalloproteinases (MMPs), may need to be rethought. Previous work suggested that inhibitors of MMPs could protect the brain, but now it seems that such inhibitors might contribute to damage (pages 441–445).

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Figure 1: Redistribution of MMP-9 within the neurovascular unit after stroke.

Katie Ris

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  1. Department of Neurosurgery, Frank P. Smith Laboratories for Neuroscience and Neurosurgical Research, University of Rochester, Rochester, 14642, New York, USA

    Berislav V Zlokovic

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  1. Berislav V Zlokovic
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Zlokovic, B. Remodeling after stroke. Nat Med 12, 390–391 (2006). https://doi.org/10.1038/nm0406-390

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