The accumulation of fibroblasts in epithelial organs such as the kidney can produce dangerous scars. Such tissue fibrosis begins when epithelial cells morph into fibroblasts by epithelial-mesenchymal transition. A key regulator of this process in the kidney now emerges (pages 387–393).
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Neilson, E. Setting a trap for tissue fibrosis. Nat Med 11, 373–374 (2005). https://doi.org/10.1038/nm0405-373
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DOI: https://doi.org/10.1038/nm0405-373
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