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…and surreal antisense?

Nature Medicine volume 2, pages 131–132 (1996)Cite this article

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References

  1. Stein, C.A. Does antisense exist?. Nature Med. 1, 1119–1121 (1995).

    Article  CAS  Google Scholar 

  2. Abe, J. et al. Suppression of neointimal smooth muscle cell accumulation in vivoby antisense cdc2 and cdk2 oligonucleotides in rat carotid artery. Biochem. Biophys. Res. Comrnun. 198, 16–24 (1994).

    Article  CAS  Google Scholar 

  3. Edelman, E.R., Simons, M., Sirois, M.G. & Rosenberg, R.D. C-myc in vasculoproiiferative disease. Circ. Res. 76, 176–182 (1995).

    Article  CAS  Google Scholar 

  4. Simons, M., Edelman, E.R. & Rosenberg, R.D. Antisense PCNA oligonucleotides inhibit intimal hyperplasia in a rat carotid injury model. J. Clin. Invest. 93, 2351–2356 (1994).

    Article  CAS  Google Scholar 

  5. Morishita, R. et al. Single intraluminal delivery of antisense cdc2 kinase and proliferating-cell nuclear antigen oligonucleotides results in chronic inhibition of neointimal hyperplasia. Proc. Natl. Acad. Sci. USA 90, 8474–8478 (1993).

    Article  CAS  Google Scholar 

  6. Sirois, M., Simons, M., Edelman, E.R., Kuter, D.J. & Rosenberg, R.D. Platelet release of platelet-derived growth factor is required for intimal hyperplasia in rat vascular injury model. Circulation 90, 1–511 (1994).

    Article  Google Scholar 

  7. Lindner, V. & Reidy, M.A. Proliferation of smooth muscle cells after vascular injury is inhibited by an antibody against basic fibroblast growth factor. Proc. Natl. Acad. Sci. USA 89, 3739–3743 (1991).

    Article  Google Scholar 

  8. Husain, M. et al. Dominant negative c-myb constructs lower intracellular calcium levels and slow cell cycle progression in vascular smooth muscle cells. Circulation 92, 1–299 (1995).

    Article  Google Scholar 

  9. Burgess, T. et al. The antiproliferative activity of c-myb and c-myc antisense oligonucleotides in smooth muscle cells is caused by a nonantisense mechanism. Proc. Natl. Acad.Sci. USA 92, 4051–4055 (1995).

    Article  CAS  Google Scholar 

  10. Villa, A. et al. Effects of antisense c-myb oligonucleotides on vascular smooth muscle cell proliferation and response to vessel wall injury. Circ. Res. 76, 505–513 (1995).

    Article  CAS  Google Scholar 

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Authors and Affiliations

  1. Department of Biology, Massachusetts Institute of Technology, Cambridge, Massachusetts, 02139, USA

    Michael Simons & Robert D. Rosenberg

  2. Department of Medicine, Beth Israel Hospital, Boston, Massachusetts, 02215, USA

    Michael Simons & Robert D. Rosenberg

  3. Department of Medicine Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, 02215, USA

    Elazer R. Edelman

  4. Department of Health, Science and Technology, Massachusetts Institute of Technology, Cambridge, Massachusetts, 02139, USA

    Elazer R. Edelman

Authors
  1. Michael Simons
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  2. Robert D. Rosenberg
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  3. Elazer R. Edelman
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Simons, M., Rosenberg, R. & Edelman, E. …and surreal antisense?. Nat Med 2, 131–132 (1996). https://doi.org/10.1038/nm0296-131b

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