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Is the LPS-mediated proteinuria mouse model relevant to human kidney disease?

Nature Medicine volume 15, pages 133–134 (2009)Cite this article

Reiser and Mundel reply:

We would like to thank Dr. Comper for his correspondence, as it allows us to provide answers for the following two questions: what is the relevance of the lipopolysaccharide (LPS) proteinuria model for human kidney disease, and did we study albumin filtration directly in the LPS, gene transfer or genetic mouse models that were described in Wei et al.1 and Faul et al.2?

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  1. Division of Nephrology and Hypertension, University of Miami Miller School of Medicine, 1580 Northwest Tenth Avenue, Batchelor Building, Sixth Floor, Miami, Florida 33136, USA. jreiser@med.miami.edu or pmundel@med.miami.edu,

    Jochen Reiser & Peter Mundel

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  1. Jochen Reiser
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  2. Peter Mundel
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Reiser, J., Mundel, P. Is the LPS-mediated proteinuria mouse model relevant to human kidney disease?. Nat Med 15, 133–134 (2009). https://doi.org/10.1038/nm0209-133b

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