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Rewiring the Parkinsonian brain

The demonstration that transplanted embryonic stem cells differentiate into functional dopamine neurons and provide stable functional recovery in a rodent model of Parkinson disease moves the field a step closer to clinical applications of embryonic stem cells.

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Figure 1: Different sources of cells used for transplantation in experimental PD and the effects of such cell grafts on functional recovery.

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Fricker-Gates, R., Dunnett, S. Rewiring the Parkinsonian brain. Nat Med 8, 105–106 (2002). https://doi.org/10.1038/nm0202-105

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