The presence of a specific amyloid β-protein in the brains of Down's syndrome patients suggests a common etiological pathway with the development of Alzheimer's disease-related neuropathology (pages 93–95).
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Tanzi, R. Neuropathology in the Down's syndrome brain. Nat Med 2, 31–32 (1996). https://doi.org/10.1038/nm0196-31
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DOI: https://doi.org/10.1038/nm0196-31