In newborn infants, permanent closure of a major blood vessel connecting the main pulmonary artery to the aorta is essential to allow adequate circulation of blood to major organs. Platelet aggregation now emerges as a crucial step in this process in newborn mice and, possibly, in preterm infants (pages 75–82).
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Clyman, R., Chemtob, S. Vessel remodeling in the newborn: platelets fill the gap. Nat Med 16, 33–35 (2010). https://doi.org/10.1038/nm0110-33
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DOI: https://doi.org/10.1038/nm0110-33
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