To the editor

Karen Birmingham's interesting article on the South African AIDS Initiative (Nature Med. 5, 1220; 1999) states that “the predominant HLA types in South Africa are presently unknown.” This ignores a succession of International Histocompatibility Workshops that have provided both HLA serological and molecular typing data for many sub-Saharan African populations.

Readers are referred to a recent article by Hammond and colleagues1, which provides an extensive molecular HLA class I and II data on many South African ethnic groups.