IgA regulates intestinal homeostasis by maintaining appropriate communities of bacteria within the gut. A new study shows that intestinal bacteria regulate metabolism via IgA (pages 1585–1593).
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Marina Corral
References
Rakoff-Nahoum, S., Paglino, J., Eslami-Varzaneh, F., Edberg, S. & Medzhitov, R. Cell 118, 229–241 (2004).
Cerutti, A., Chen, K. & Chorny, A. Annu. Rev. Immunol. 29, 273–293 (2011).
Hapfelmeier, S. et al. Science 328, 1705–1709 (2010).
Benckert, J. et al. J. Clin. Invest. 121, 1946–1955 (2011).
Peterson, D.A., McNulty, N.P., Guruge, J.L. & Gordon, J.I. Cell Host Microbe 2, 328–339 (2007).
Fagarasan, S. et al. Science 298, 1424–1427 (2002).
Wei, M. et al. Nat. Immunol. 12, 264–270 (2011).
Shulzhenko, N. et al. Nat. Med. 17, 1585–1593 (2011).
He, B. et al. Immunity 26, 812–826 (2007).
Macpherson, A.J. & Uhr, T. Science 303, 1662–1665 (2004).
Malamut, G. et al. Am. J. Gastroenterol. 105, 2262–2275 (2010).
Vijay-Kumar, M. et al. Science 328, 228–231 (2010).
Uematsu, S. et al. Nat. Immunol. 9, 769–776 (2008).
Round, J.L. & Mazmanian, S.K. Nat. Rev. Immunol. 9, 313–323 (2009).
Xu, W. et al. Nat. Immunol. 10, 1008–1017 (2009).
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Chorny, A., Cerutti, A. A gut triumvirate rules homeostasis. Nat Med 17, 1549–1550 (2011). https://doi.org/10.1038/nm.2592
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DOI: https://doi.org/10.1038/nm.2592
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