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RIG-I-like antiviral protein in flies

The function of gene expression in the response of drosophila to viral infection is poorly understood. A report now demonstrates that the helicase Dicer-2 controls antiviral gene expression in addition to RNA interference–mediated gene silencing.

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Figure 1: Dual function for Dicer-2 in antiviral immunity.

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Takeuchi, O., Akira, S. RIG-I-like antiviral protein in flies. Nat Immunol 9, 1327–1328 (2008). https://doi.org/10.1038/ni1208-1327

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