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Mast cells to the defense

Mast cells are not only important in IgE-associated disorders but also contribute to host defense against bacteria. One way they do this is by enhancing T cell recruitment and lymph node enlargement during bacterial infection.

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Figure 1: Diverse potential contributions of mast cells during innate and acquired immunity, and in other biological responses.

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Galli, S., Nakae, S. Mast cells to the defense. Nat Immunol 4, 1160–1162 (2003). https://doi.org/10.1038/ni1203-1160

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