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Outfoxing Foxo1 with miR-182

Nature Immunology volume 11, pages 983–984 (2010)Cite this article

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Induction of the microRNA miR-182 by interleukin 2 in helper T lymphocytes targets the transcription factor Foxo1 and promotes clonal expansion. Targeting this process opens new possibilities for adjuvancy, immunosuppression and anti-inflammatory therapeutics.

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Figure 1: Regulation of the clonal expansion of helper T cells by miR-182.

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  1. Luke A.J. O'Neill is in the School of Biochemistry and Immunology, Trinity College Dublin, Ireland.,

    Luke A J O'Neill

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  1. Luke A J O'Neill
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Correspondence to Luke A J O'Neill.

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The author declares no competing financial interests.

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O'Neill, L. Outfoxing Foxo1 with miR-182. Nat Immunol 11, 983–984 (2010). https://doi.org/10.1038/ni1110-983

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