L-selectin expressed by lymphocytes interacts with specialized glycans on endothelium to mediate lymphocyte rolling. Two sulfotransferases that act cooperatively to add sulfate esters to a specific sugar residue on glycans are critical for this process.
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McEver, R. A sulfated address for lymphocyte homing. Nat Immunol 6, 1067–1069 (2005). https://doi.org/10.1038/ni1105-1067
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DOI: https://doi.org/10.1038/ni1105-1067