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Beating a kinase?

All kinases must be tightly regulated. Isolation of a novel molecule called IBtk identifies a potential mechanism for the regulation of Bruton's tyrosine kinase in B cells.

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Figure 1: Btk-binding molecules and possible mechanisms for regulation of Btk activity.

Bob Crimi

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Koyasu, S. Beating a kinase?. Nat Immunol 2, 897–898 (2001). https://doi.org/10.1038/ni1001-897

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