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T cells: getting a GRP on Ras

Nature Immunology volume 1, pages 275–276 (2000)Cite this article

Activation of Ras is key for lymphocyte development and function. The understanding of Ras activation in T cells now takes an important step forward by the initial analysis of mice lacking the Ras activator RasGRP.

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Figure 1: A model for Ras activation in T cells.

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Authors and Affiliations

  1. Department of Medicine and The Howard Hughes Medical Institute, University of California, San Francisco, 94143-0795, CA, USA

    Jeroen Roose & Arthur Weiss

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  1. Jeroen Roose
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  2. Arthur Weiss
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Roose, J., Weiss, A. T cells: getting a GRP on Ras. Nat Immunol 1, 275–276 (2000). https://doi.org/10.1038/79713

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