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T cell memory: fixed or flexible?

Nature Immunology volume 6, pages 752–754 (2005)Cite this article

Contrary to results of previous studies using high frequencies of T cell receptor–transgenic T cells, new data indicate that when naive precursor frequencies approach endogenous levels, CD8+ effector and central memory T cell lineage commitment is fixed.

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Figure 1: The effect of naive precursor frequency on memory T cell differentiation.

Katie Ris

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Authors and Affiliations

  1. Department of Immunology and Howard Hughes Medical Institute at the University of Washington, Seattle, 98155, Washington, USA

    Matthew A Williams & Michael J Bevan

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  1. Matthew A Williams
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  2. Michael J Bevan
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Williams, M., Bevan, M. T cell memory: fixed or flexible?. Nat Immunol 6, 752–754 (2005). https://doi.org/10.1038/ni0805-752

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