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The CD1b structure: antigen presentation adapts to a high-fat diet

CD1b protein presents glycolipids of various tail lengths to T cells. The crystal structure of CD1b sheds light on its ability to accommodate these different glycolipids.

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Figure 1: The family of MHC class I–related lipid-binding proteins.

Bob Crimi

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Niazi, K., Porcelli, S. & Modlin, R. The CD1b structure: antigen presentation adapts to a high-fat diet. Nat Immunol 3, 703–704 (2002). https://doi.org/10.1038/ni0802-703

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