Much vaccine research is directed toward the generation of more effective vaccines. By combining DNA vaccines with the innate immune system, a flu vaccine was designed that required only a single immunization.
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Fearon, D. Innate immunity—beginning to fulfill its promise?. Nat Immunol 1, 102–103 (2000). https://doi.org/10.1038/77773
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DOI: https://doi.org/10.1038/77773