The disappearance of CD4+ T cells during an HIV infection sets the stage for the characteristic immunodeficiency. But how do the virally infected cells protect themselves long enough to manufacture more HIV virions? A recent paper in Nature suggests that Nef may be part of the answer.
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Bob Crimi
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Xu, X., Screaton, G. HIV-1 Nef: negative effector of Fas?. Nat Immunol 2, 384–385 (2001). https://doi.org/10.1038/87682
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DOI: https://doi.org/10.1038/87682
