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Crawling and INTEGRating apical cues

Nature Immunology volume 5, pages 351–353 (2004)Cite this article

Leukocytes are arrested on endothelial cells before moving through vessel intercellular junctions. The identification of another β2 integrin–dependent step may provide insights into the events and signals required for transmigration.

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Figure 1: Monocyte locomotion on vascular endothelium: directional transport to the site of transmigration (TEM) and an 'educational' process for essential leukocyte and endothelial cell polarization.

K.R.

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Authors and Affiliations

  1. Department of Immunology, The Weizmann Institute of Science, Rehovot, 76100, Israel

    Ronen Alon

  2. Department of Pathology, Center for Excellence in Vascular Biology, Brigham and Women's Hospital, Boston, 02115, Massachusetts, USA

    Francis W Luscinskas

Authors
  1. Ronen Alon
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  2. Francis W Luscinskas
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Alon, R., Luscinskas, F. Crawling and INTEGRating apical cues. Nat Immunol 5, 351–353 (2004). https://doi.org/10.1038/ni0404-351

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