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Vanilloid flavor for a good appetite?

Members of the transient receptor potential vanilloid ion-channel family are expressed in a wide variety of cells and function as sensors of mechanical stress. The second such family member, TVRP2, is now also linked to phagocytosis in macrophages.

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Figure 1: A model for the cooperation between TRPV2 and FcγR in triggering phagocytosis.

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Correspondence to Shigeo Koyasu.

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Koyasu, S. Vanilloid flavor for a good appetite?. Nat Immunol 11, 187–189 (2010). https://doi.org/10.1038/ni0310-187

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