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Langerhans cells: daughters of monocytes

Precursors of specialized skin dendritic cells called Langerhans cells are derived from specific bone marrow–derived monocyte precursors that migrate to the skin and differentiate into these important immune surveillance cells.

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Figure 1: The road to LC immunity.

Katie Ris

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Palucka, A., Banchereau, J. Langerhans cells: daughters of monocytes. Nat Immunol 7, 223–224 (2006). https://doi.org/10.1038/ni0306-223

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