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New look at an old costimulator

The long-awaited structure of CD28 provides new understanding of its function and opens new avenues for probing this important costimulatory molecule.

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Figure 1: Signaling properties of CD28 after triggering with a natural ligand or different types of mAbs.

K.R.

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Linsley, P. New look at an old costimulator. Nat Immunol 6, 231–232 (2005). https://doi.org/10.1038/ni0305-231

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