Resting dendritic cells can induce T cell tolerance. This process requires engagement of the costimulatory molecules PD-1 and CTLA-4 on T cells.
This is a preview of subscription content, access via your institution
Access options
Subscribe to this journal
Receive 12 print issues and online access
$209.00 per year
only $17.42 per issue
Rent or buy this article
Prices vary by article type
from$1.95
to$39.95
Prices may be subject to local taxes which are calculated during checkout
References
Probst, H.C., Lagnel, J., Kollias, G. & van den Broek, M. Immunity 18, 713–720 (2003).
Probst, H.C. et al. Nat. Immunol. 6, 280–286 (2005).
Hawiger, D. et al. J. Exp. Med. 194, 769–779 (2001).
Steinman, R.M., Hawiger, D. & Nussenzweig, M.C. Annu. Rev. Immunol. 21, 685–711 (2003).
Moser, M. Immunity 19, 5–8 (2003).
Schwartz, R.H. Annu. Rev. Immunol. 21, 305–334 (2003).
Perez, V.L. et al. Immunity 6, 411–417 (1997).
Greenwald, R.J., Boussiotis, V.A., Lorsbach, R.B., Abbas, A.K. & Sharpe, A.H. Immunity 14, 145–155 (2001).
Latchman, Y.E. et al. Proc. Natl. Acad. Sci. USA 101, 10691–10696 (2004).
Bennett, F. et al. J. Immunol. 170, 711–718 (2003).
Salomon, B. & Bluestone, J.A. Annu. Rev. Immunol. 19, 225–252 (2001).
Lohr, J., Knoechel, B., Jiang, S., Sharpe, A.H. & Abbas, A.K. Nat. Immunol. 4, 664–669 (2003).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Abbas, A., Sharpe, A. Dendritic cells giveth and taketh away. Nat Immunol 6, 227–228 (2005). https://doi.org/10.1038/ni0305-227
Issue Date:
DOI: https://doi.org/10.1038/ni0305-227
This article is cited by
-
Reviews and comment from the nature publishing group
Nature Reviews Immunology (2005)
-
Immune restoration following hematopoietic stem cell transplantation: an evolving target
Bone Marrow Transplantation (2005)