When acetyl or methyl groups are added to histones, chromatin structure and gene expression are altered. The methyltransferase G9a can target the specific silencing of IFNB gene expression and blocking of V(D)J recombination.
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Makar, K., Wilson, C. Sounds of a silent Blimp-1. Nat Immunol 5, 241–242 (2004). https://doi.org/10.1038/ni0304-241
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DOI: https://doi.org/10.1038/ni0304-241