The thymus is considered the source of mature lymphocytes and is not thought to produce progenitors with the capacity to develop into unconventional T cells in the periphery. That view requires revision.
This is a preview of subscription content, access via your institution
Access options
Subscribe to this journal
Receive 12 print issues and online access
$209.00 per year
only $17.42 per issue
Buy this article
- Purchase on Springer Link
- Instant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout
References
Macpherson, A.J. et al. Immunology 115, 153–162 (2005).
Hayday, A. et al. Nat. Immunol. 2, 997–1003 (2001).
Rocha, B. et al. J. Exp. Med. 173, 483–486 (1991).
Lambolez, F. et al. Nat. Immunol. 7, 76–82 (2006).
Poussier, P. et al. J. Exp. Med. 195, 1491–1497 (2002).
Silva-Santos, B. et al. Science 307, 925–928 (2005).
Harman, B. et al. Blood 106, 886–892 (2005).
Laky, K. et al. J.Exp. Med. 191, 1569–1580 (2000).
Guy-Grand, D. et al. J. Exp. Med. 197, 333–341 (2003).
Bas, A. et al. J. Immunol. 171, 3359–3371 (2003).
Eberl, G. & Littman, D.R. Science 305, 248–251 (2004).
Leishman, A. et al. Immunity 16, 355–364 (2002).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Hayday, A. Orchestrated leak provokes a thymus reassessment. Nat Immunol 7, 9–11 (2006). https://doi.org/10.1038/ni0106-9
Issue Date:
DOI: https://doi.org/10.1038/ni0106-9
This article is cited by
-
Key factors in the organized chaos of early T cell development
Nature Immunology (2007)