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Self-help in T cell recognition?

Nature Immunology volume 3, pages 11–12 (2002)Cite this article

Activation of T cells requires TCR engagement of foreign peptide complexed with MHC. New evidence suggests that TCR engagement of self-peptide–MHC complexes may enhance recognition of foreign antigen.

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Figure 1: Contribution of weak TCR ligands to T cell antigen recognition.

Bob Crimi

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Authors and Affiliations

  1. Sir William Dunn School of Pathology, University of Oxford, Oxford, OX1 3RE, UK

    Talitha R. Bakker & P. Anton van der Merwe

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  1. Talitha R. Bakker
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  2. P. Anton van der Merwe
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Bakker, T., van der Merwe, P. Self-help in T cell recognition?. Nat Immunol 3, 11–12 (2002). https://doi.org/10.1038/ni0102-11

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