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ILC2s masquerade as ILC1s to drive chronic disease

Nature Immunology volume 17, pages 611–612 (2016)Cite this article

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Tissue-resident innate lymphoid cells (ILCs) perform diverse roles in regulating mucosal homeostasis and inflammation. The transdifferentiation of ILC2s into interferon-γ (IFN-γ)-producing ILC1-like cells generates a highly inflammatory immune cell.

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Figure 1: Programs of plasticity in ILC2 and ILC3.

Katie Vicari/Nature Publishing Group

Change history

  • 02 June 2016

    In the version of this News & Views initially published, an incorrect article (Ohne et al.; ref. 2) was cited in the third sentence of the penultimate paragraph, and in the fifth sentence of that paragraph, ILCs were reported as being isolated from patients with chronic obstructive pulmonary disease. The correct citation is Silver et al. (ref. 3), and the cells should be described as being derived in vitro from healthy donors. The errors have been corrected in the HTML and PDF versions of the article.

References

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Authors and Affiliations

  1. Gabrielle T. Belz is with the Walter and Eliza Hall Institute of Medical Research, Melbourne, Australia.,

    Gabrielle T Belz

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  1. Gabrielle T Belz
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Correspondence to Gabrielle T Belz.

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Belz, G. ILC2s masquerade as ILC1s to drive chronic disease. Nat Immunol 17, 611–612 (2016). https://doi.org/10.1038/ni.3467

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