Thymic selection shapes the repertoire of potentially autoreactive thymocytes that are allowed to mature. The expression pattern of self antigen seen by thymocytes determines the number and functional ability of autoreactive T cells.
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Millar, D., Ohashi, P. Central tolerance: what you see is what you don't get!. Nat Immunol 17, 115–116 (2016). https://doi.org/10.1038/ni.3373
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DOI: https://doi.org/10.1038/ni.3373
