The RNA endonuclease Drosha is required for myelopoiesis by its direct cleavage of stem-loop structures in mRNAs encoding Myl9 and Todr1.
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References
Ha, M. & Kim, V.N. Nat. Rev. Mol. Cell Biol. 15, 509–524 (2014).
Johanson, T.M. et al. Nat. Immunol. 16, 1134–1141 (2015).
Doulatov, S., Notta, F., Laurenti, E. & Dick, J.E. Cell Stem Cell 10, 120–136 (2012).
Johanson, T.M., Lew, A.M. & Chong, M.M.W. Open Biology 3, 1–9 (2013).
Han, J. et al. Cell 136, 75–84 (2009).
Knuckles, P. et al. Nat. Neurosci. 15, 962–969 (2012).
Chong, M.M.W. et al. Genes Dev. 24, 1951–1960 (2010).
Karginov, F.V. et al. Mol. Cell 38, 781–788 (2010).
Shapiro, J.S. et al. Proc. Natl. Acad. Sci. USA 111, 7108–7113 (2014).
Lin, Y.-T. & Sullivan, C.S. Proc. Natl. Acad. Sci. USA 108, 11229–11234 (2011).
Macias, S. et al. Nat. Struct. Mol. Biol. 19, 760–766 (2012).
Cheloufi, S. Santos, Dos, C.O., Chong, M.M.W. & Hannon, G.J. Nature 465, 584–589 (2010).
Cifuentes, D. et al. Science 328, 1694–1698 (2010).
Gromak, N. et al. Cell Rep. 5, 1499–1510 (2013).
Alarcón, C.R., Lee, H., Goodarzi, H., Halberg, N. & Tavazoie, S.F. Nature 519, 482–485 (2015).
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van der Veen, A., Maillard, P. & Reis e Sousa, C. Drosha cuts the tethers of myelopoiesis. Nat Immunol 16, 1110–1112 (2015). https://doi.org/10.1038/ni.3297
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DOI: https://doi.org/10.1038/ni.3297