Targeted deletion of the transcription factor XBP1 in hematopoietic stem cells selectively prevents eosinophil maturation in the bone marrow without affecting other lineages of the immune system.
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Shen, ZJ., Malter, J. XBP1, a determinant of the eosinophil lineage. Nat Immunol 16, 793–794 (2015). https://doi.org/10.1038/ni.3214
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DOI: https://doi.org/10.1038/ni.3214
