The interaction between hematopoietic stem cells and their niche is critical for the lifelong maintenance of the blood system. New research shows that crosstalk between stromal components of the niche mediates secretion of the chemokine CXCL12.
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References
Ehninger, A. & Trumpp, A. J. Exp. Med. 208, 421–428 (2011).
Mendez-Ferrer, S. et al. Nature 466, 829–834 (2010).
Omatsu, Y. et al. Immunity 33, 387–399 (2010).
Schajnovitz, A. et al. Nat. Immun. 12, 391–398 (2011).
Cancelas, J.A. et al. Blood 96, 498–505 (2000).
Presley, C.A. et al. Cell Commun. Adhes. 12, 307–317 (2005).
Sacchetti, B. et al. Cell 131, 324–336 (2007).
Wilson, A. & Trumpp, A. Nat. Rev. Immunol. 6, 93–106 (2006).
Qian, H. et al. Cell Stem Cell 1, 671–684 (2007).
Kiel, M.J., Yilmaz, O.H., Iwashita, T., Terhorst, C. & Morrison, S.J. Cell 121, 1109–1121 (2005).
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Milsom, M., Trumpp, A. Bridging the information gap. Nat Immunol 12, 377–379 (2011). https://doi.org/10.1038/ni.2026
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DOI: https://doi.org/10.1038/ni.2026
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