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A leukemogenic twist for GATA1

Mutations in the gene encoding the transcription factor GATA1 contribute to a specific type of leukemia in people with Down syndrome. This finding suggests a multistep pathway of leukemia development that involves GATA1 and one or more genes on chromosome 21.

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Look, A. A leukemogenic twist for GATA1. Nat Genet 32, 83–84 (2002). https://doi.org/10.1038/ng960

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