Sequencing of genomes, including that of humans, has revolutionized our understanding of genome organization and accelerated the hunt for disease-causing mutations. New studies by the Human Epigenome Project (HEP) now highlight the importance and complexity of cytosine DNA methylation in tissue-specific regulation of gene expression.
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Brena, R., Huang, TM. & Plass, C. Toward a human epigenome. Nat Genet 38, 1359–1360 (2006). https://doi.org/10.1038/ng1206-1359
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DOI: https://doi.org/10.1038/ng1206-1359
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