Erratum: Inversin, a novel gene in the vertebrate left-right axis pathway, is partially deleted in the inv mouse

Nature Genetics 20, 149– 156 (1998).

Due to a printing error, accurate reproduction of Figure 1 was compromised. The correct version is printed below.

Fig. 1 Genomic organization of the mouse Invs gene and cDNA contig assembly. a, Schematic of wild-type and inv chromosome 4. Transgene insertion involved integration of two copies of a tyrosinase minigene, deletion of a 47-kb sequence and duplication of a short segment initially located 6 cM distal to the region that was deleted. b, Organization of YAC and BAC clones spanning the region deleted in the inv mouse. A, ApaI; B, BssHII; E, EagI; M, MluI; N, NotI; Na, NarI; Nh, NheI; S, SmaI; X, XhoI. Sequence contigs 82/2145 and 1908 are derived from clone BAC394-P2, which spans the deleted region. c, Exon/intron organization of the Invs gene spanning the deleted region. d, cDNA contig assembly. Vertical lines in the bar at top indicate position of exon boundaries in the cDNA sequence and horizontal lines below indicate individual cDNA clones. Clones obtained by RT-PCR and RACE are indicated by the prefix 'RT' or 'RA', respectively, and were obtained using mouse adult liver cDNA; sources of clones obtained by standard cDNA library screening are as follows: Ccl, Clontech mouse adult liver; pKE15-5, E15.0 mouse kidney; 583066, Soares 2NbMT mouse thymus; and 636902, Soares NbMLN mouse lymph cDNA. Alternative splicing in exon 13 to give transcripts lacking a 360- or a 495-nt sequence (Fig. 5) is indicated by an inverted V. ATG, translation initiation codon; Ter, stop codon; pA1, pA2, alternative polyadenylation signals.