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Infectious diseases not immune to genome-wide association

Two genome-wide association studies for meningococcal disease and tuberculosis identify new loci associated with susceptibility to these infectious diseases. They highlight a role for the acquired and innate immune systems in host control of several human pathogens and demonstrate that denser genotyping platforms and population-specific reference panels are necessary for genetic studies in African populations.

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Correspondence to Paul I W de Bakker or Amalio Telenti.

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de Bakker, P., Telenti, A. Infectious diseases not immune to genome-wide association. Nat Genet 42, 731–732 (2010). https://doi.org/10.1038/ng0910-731

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