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Unlocking the pathogenesis of celiac disease

A genome-wide association study reports more than a dozen new susceptibility loci for celiac disease. Analysis of eQTL data from these and previously established risk loci sheds light on the genetic pathways underlying this common autoimmune disease.

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Figure 1: Mechanisms underlying celiac disease pathogenesis.

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Correspondence to Robert M Plenge.

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The author declares no competing financial interests.

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Plenge, R. Unlocking the pathogenesis of celiac disease. Nat Genet 42, 281–282 (2010). https://doi.org/10.1038/ng0410-281

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