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Genetics of cardiac repolarization

Nature Genetics 41, 388–389 (2009) | Download Citation

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Prolongation of the electrocardiographic QT interval, a measure of cardiac repolarization, is associated with arrhythmogenic disorders and is a risk factor for sudden cardiac death. Two genome-wide association studies (GWAS) of variation in the QT interval in population-based cohorts now report association with variants in a subset of ion channel genes and other new associations.

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Affiliations

  1. Svati H. Shah and Geoffrey S. Pitt are in the Department of Medicine, Division of Cardiology, Duke University Medical Center, Durham, North Carolina, USA. svati.shah@duke.edu

    • Svati H Shah
    •  & Geoffrey S Pitt

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DOI

https://doi.org/10.1038/ng0409-388

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