The impact of microarray technology on biology will depend on computational methods of data analysis. A supervised computer-learning method using support vector machines predicts gene function from expression data—and shows promise.
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References
Brazma, A. Report on the first international meeting on microarray gene expression databases (MGED); http://www.ebi.ac.uk/microarray/MGED/
Brown, M.P.S. et al. Proc. Natl Acad. Sci. USA 97, 262– 267 (2000).
Ben-Dor, M., Shamir, R. & Yakhini, Z. J. Comp. Biol. 6, 281– 297 (1999).
Raychaudhuri, S., Stuart, J. & Altman, R. in Proceedings of the Pacific Symposium on Biocomputing 452–463 (Honolulu, Hawaii, 2000).
Kohonen, T. Self-organizing maps (Springer Verlag, Heidelberg, 1997).
VanBoegelen, R., Schiller, E., Thomas, J. & Neidhardt, F. Electrophoresis 20, 2149–2159 ( 1999).
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Gaasterland, T., Bekiranov, S. Making the most of microarray data. Nat Genet 24, 204–206 (2000). https://doi.org/10.1038/73392
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DOI: https://doi.org/10.1038/73392
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